Interaction of Mannitol and Sucrose with Gellan Gum in Freeze-Dried Gel Systems
نویسندگان
چکیده
منابع مشابه
Controlling the physical form of mannitol in freeze-dried systems.
A potential drawback with the use of mannitol as a bulking agent is its existence as mannitol hemihydrate (MHH; C₆H₁₄O₆·0.5H₂O) in the lyophile. Once formed during freeze-drying, MHH dehydration may require secondary drying under aggressive conditions which can be detrimental to the stability of thermolabile components. If MHH is retained in the lyophile, the water released by MHH dehydration d...
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The objective of this study was to develop soft paracetamol gel using gellan gum as a gelling agent and sodium citrate as a source of cation. Different batches were prepared using three different concentrations of gellan gum (0.1, 0.3, and 0.5%), each with two different sodium citrate concentrations (0.3 and 0.5%). The consistency of the paracetamol gel was dependent on the concentration of gel...
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Polysaccharide is used widely in food, cosmetic and pharmaceutical industries. The main use is to give appropriate texture to the products. Thus the polysaccharides used in such way are called texture modifier. Here two important texture modifiers, gellan and tamarind xyloglucan are introduced. The former one is a microbial polysaccharide with gelling ability. Gelling ability makes gellan valua...
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Prolonged residence of drug formulation in the nasal cavity is important for the enhancing intranasal drug delivery. The objective of the present study was to develop a mucoadhesive in-situ gelling nasal insert which would enable the reduced nasal mucociliary clearance in order to improve the bioavailability of metoclopramide hydrochloride. Metoclopramide hydrochloride is a potent antiemetic...
متن کاملFreeze-dried Xanthan/Guar Gum Nasal Inserts for the Delivery of Metoclopramide Hydrochloride
Prolonged residence of drug formulation in the nasal cavity is important for the enhancing intranasal drug delivery. The objective of the present study was to develop a mucoadhesive in-situ gelling nasal insert which would enable the reduced nasal mucociliary clearance in order to improve the bioavailability of metoclopramide hydrochloride. Metoclopramide hydrochloride is a potent antiemetic...
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ژورنال
عنوان ژورنال: Food Biophysics
سال: 2018
ISSN: 1557-1858,1557-1866
DOI: 10.1007/s11483-018-9536-5